RU58841 — 5% (30 ml) • Local DHT Defense
Wed Nov 12 2025 00:00:00 GMT+0000 (Coordinated Universal Time)
Educational use only — not medical advice.
What It Does
RU58841 is a topical research compound that binds androgen receptors in the scalp and blocks DHT locally, helping protect follicles without detouring systemic hormones. That’s why I use it alongside inflammation control and mitochondrial support...
Carrier Options
- 70/30 Ethanol : Propylene Glycol — DIY, fast-drying, strong penetration.
- Anageninc K&B — pre-mixed carrier; add powder → shake → done.
Skin varies. If one carrier irritates, try the other.
Target Batch • 30 ml @ 5% (≈ 50 mg/ml)
- RU58841 powder: 1.50 g
- Ethanol: 21 ml
- Propylene Glycol: 9 ml
You’ll Need
Accurate 0.01 g scale • 2×50 ml beakers • glass stir rod • small funnel • 30–50 ml amber bottle (dropper or reducer).
Instructions (70/30 EtOH/PG)
- Measure 21 ml ethanol (beaker A) and 9 ml PG (beaker B).
- Tare the scale to 0 with an empty beaker; weigh 1.50 g RU58841 into it.
- Add ethanol to the powder; stir to dissolve.
- Add PG; stir until crystal clear (no particulates).
- If hazy, add a small amount more vehicle keeping 70/30 (e.g., +0.7 ml EtOH + 0.3 ml PG), then stir again.
- Funnel to an amber bottle. Label:
RU58841 • 5% • 30 ml • ~50 mg/ml • YYYY-MM-DD
Fastest Route (Anageninc K&B)
- Pour 30 ml K&B into a bottle.
- Add 1.50 g RU58841.
- Cap and shake lightly until uniform.
Storage
- Powder: freezer (sealed, moisture-proof).
- Mixed solution: fridge, dark (amber), minimal headspace.
- Room temp is possible short-term but shortens shelf life.
Spacing With Other Topicals (general guidance, not advice)
Apply once daily to clean, dry scalp. Start 0.5–1.0 ml; adjust by coverage. If stacking (e.g., GHK-Cu, minoxidil), separate by 15–30 min.
Why I Use Anageninc
Consistent carrier quality, less mess, and repeatable batches. K&B removes solvent hunting and keeps the process tight.
Protocol V Takeaway
Goal: Tactical follicle defense with high repeatability.
Recipe: 1.50 g RU + 21 ml EtOH + 9 ml PG → 30 ml @ 5%.
When I want speed and simplicity, I use Anageninc K&B.